Anti-mitochondrial antibody

Anti-mitochondrial antibodies (AMA) are antibodies (immunoglobulins) formed against mitochondria,^[1] primarily mitochondria in cells of the liver. The presence of AMAs in the blood or serum of a person is indicative of a disease called primary biliary cirrhosis (PBC)^[2] (a scarring of liver tissue, confined primarily to the bile duct drainage system of the liver). It is present in about 95% of cases.^[3]