Biotransformation



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Biotransformation is the chemical modification (or modifications) made by an organism. If this modification ends in mineral compounds like CO2, NH3+ or H2O, the biotransformation is called mineralisation.

Microbial biotransformation

Biotransformation of various biodegradative pathways and the ability of organisms to adapt to changing environmental conditions.

Biological processes play a major role in the removal of bioremediation technologies and biotransformation processes.[1] Also there is other approach of biotransformation called enzymatic biotransformation.

Oil Biodegradation

Petroleum oil is toxic for most life forms and episodic and chronic biocatalysis.[2]

Metabolic Engineering and Biocatalytic Applications

The study of the fate of persistent organic chemicals in the environment has revealed a large reservoir of enzymatic reactions with a large potential in preparative organic synthesis, which has already been exploited for a number of oxygenases on pilot and even on industrial scale. Novel catalysts can be obtained from metagenomic libraries and biodegradation. In many cases, these catalysts need to be exploited in whole cell bioconversions or in fermentations, calling for system-wide approaches to understanding strain physiology and metabolism and rational approaches to the engineering of whole cells as they are increasingly put forward in the area of systems biotechnology and synthetic biology.[3]

See also

References

  1. ^ a b Diaz E (editor). (2008). Microbial Biodegradation: Genomics and Molecular Biology, 1st ed., Caister Academic Press. ISBN 978-1-904455-17-2. 
  2. ^ Martins VAP et al (2008). "Genomic Insights into Oil Biodegradation in Marine Systems", Microbial Biodegradation: Genomics and Molecular Biology. Caister Academic Press. ISBN 978-1-904455-17-2. 
  3. ^ Meyer A and Panke S (2008). "Genomics in Metabolic Engineering and Biocatalytic Applications of the Pollutant Degradation Machinery", Microbial Biodegradation: Genomics and Molecular Biology. Caister Academic Press. ISBN 978-1-904455-17-2. 
 
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