Mepivacaine



Mepivacaine
Systematic (IUPAC) name
N-(2,6-dimethylphenyl)- 1-methyl-piperidine-2-carboxamide
Identifiers
CAS number 96-88-8
ATC code N01BB03
PubChem 4062
DrugBank APRD01094
Chemical data
O 
Mol. mass 246.348 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

C, use w/ caution, may cause fetal bradycardia

Legal status
Routes  ?

Mepivacaine (procaine) and medium duration of action (shorter than that of procaine) and is marketed under various trade names including Carbocaine and Polocaine.

Mepivacaine became available in the United States in the 1960s.

Mepivacaine is used in local infiltration and regional anesthesia. It is chemically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)

 
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