Cloxacillin



Cloxacillin
Systematic (IUPAC) name
(2S,5R,6R)-6-{[3-(2-chlorophenyl)-5-methyl-
oxazole-4-carbonyl]amino}-3,3-dimethyl-7-oxo-
4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Identifiers
CAS number 61-72-3
ATC code J01CF02
PubChem 6098
DrugBank APRD00882
Chemical data
S 
Mol. mass 435.882 g/mol
Pharmacokinetic data
Bioavailability 37 to 90%
Protein binding 95%
Metabolism  ?
Half life 30 minutes to 1 hour
Excretion Renal and biliary
Therapeutic considerations
Pregnancy cat.

B(US)

Legal status
Routes Oral, IM

Cloxacillin is a semisynthetic penicillin. It is sold under a number of trade names, including Cloxapen and Orbenin. Cloxacillin is used against staphylococci that produce beta-lactamase.

This drug has a weaker antibacterial activity than benzylpencillin, and is devoid of serious toxicity except for allergic reactions.

See also

v • d • e
Co-amoxiclav
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cloxacillin". A list of authors is available in Wikipedia.