Dimercaptosuccinic acid



Dimercaptosuccinic acid
Systematic (IUPAC) name
2,3-bis-sulfanylbutanedioic acid
Identifiers
CAS number 304-55-2
ATC code  ?
PubChem 9354
DrugBank APRD01236
Chemical data
S2 
Mol. mass 182.22 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 48 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

Dimercaptosuccinic_acid

Routes  ?

  Dimercaptosuccinic acid, or DMSA, is the chelating agent.

Meso 2,3-dimecaptosuccinic acid is used to sequester heavy metals such as blood-brain barrier, and thus is useful for extracting heavy metals from the brain.[1]

DMSA is also called succimer and is sold under the brand name Chemet®. The dimethylester is also known.[2]

References

  1. ^ Aasath, Jan; Dag Jacobsen, Ole Andersen, Elsa Wickstrøm (March 1995). "Treatment of Mercury and Lead Poisonings with Dimercaptosuccinic Acid (DMSA) and Sodium Dimercaptopropanesulfonate (DMPS)". Analyst 120: 853ff.
  2. ^ M. Gerecke, E. A. H. Friedheim, A. Brossi (1961). "Zur Kenntnis der 2,3-Dimercapto-bernsteinsäuren". Helvetica Chimca Acta: 955-960. doi:10.1002/hlca.19610440410.

See also
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Dimercaptosuccinic_acid". A list of authors is available in Wikipedia.