Edrophonium



Edrophonium
Systematic (IUPAC) name
ethyl-(3-hydroxyphenyl)-dimethyl-ammonium
Identifiers
CAS number 116-38-1
ATC code  ?
PubChem 3202
DrugBank APRD00944
Chemical data
O+
Mol. mass 166.24 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Edrophonium is a readily reversible acetylcholinesterase inhibitor. It prevents breakdown of the acetylcholine and acts by competitively inhibiting the enzyme acetylcholinesterase, mainly at the neuromuscular junction. It is sold under the trade names Tensilon, Enlon and Reversol.

Clinical uses

Because its duration of action is only about 10 minutes, edrophonium (by the so-called depolarizing block.

Sources

  1. Brenner, G. M. (2000). Pharmacology. Philadelphia, PA: W.B. Saunders Company. ISBN 0-7216-7757-6
  2. Canadian Pharmacists Association (2000). Compendium of Pharmaceuticals and Specialties (25th ed.). Toronto, ON: Webcom. ISBN 0-919115-76-4
v • d • e
Tacrine - Edrophonium
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Edrophonium". A list of authors is available in Wikipedia.