Fanconi syndrome



Fanconi syndrome
Classification & external resources
ICD-10 E72.0
ICD-9 270.0
DiseasesDB 11687
eMedicine ped/756 
MeSH D005198

Fanconi Syndrome (also known as Fanconi's syndrome) is a disorder in which the proximal tubular function of the kidney is impaired, resulting in decreased reabsorption of bicarbonate.

The reduced reabsorption of bicarbonate results in type 2 or proximal renal tubular acidosis, which may in some cases exist on its own, or more usually in combination with the Fanconi syndrome.

It is named after Guido Fanconi, a Swiss pediatrician; this may be a misnomer since Fanconi himself never identified it as a syndrome.

It should not be confused with Fanconi anemia, a separate disease.

Clinical features

Main article: renal tubular acidosis

Are the clinical features of proximal renal tubular acidosis:

And the other features of the generalised proximal tubular dysfunction of the Fanconi syndrome

Causes

There are different diseases underlying Fanconi syndrome. They can be inherited/congenital as well as acquired. tenofovir.

Treatment

Treatment of children with Fanconi syndrome mainly consists of replacement of substances lost in the urine (mainly fluid and bicarbonate).

See also

  • Familial renal disease in animals for Fanconi syndrome in Basenjis
v • d • e
PDHA) - Krabbe disease
Abetalipoproteinemia
Fatty acid: Adrenoleukodystrophy - Acyl-coA dehydrogenase (Acatalasia
v • d • e
Urinary system - Nephrogenic diabetes insipidus - Renal tubular acidosis - Nephroptosis - Ureterocele
Other diseases and
disorders of urinary system		urinary bladder: Cystitis (Interstitial cystitis, Trigonitis) - Neurogenic bladder - Vesicointestinal fistula

urethra: Urethritis (Non-gonococcal urethritis) - Urethral syndrome - Urethral stricture

Urinary tract infection
Tumors of the kidneyRenal cell carcinoma - Wilms' tumor (children)
See also congenital conditions (Q60-Q64, 753)
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Fanconi_syndrome". A list of authors is available in Wikipedia.