Her 4



v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
Identifiers
Symbol ERBB4
Entrez 2066
HUGO 3432
OMIM 600543
RefSeq NM_001042599
UniProt Q15303
Other data
Locus Chr. 2 q34

Her-4, more commonly called ErbB4, is a member of the epidermal growth factor receptor, Her-4 is able to bind to several activating ligands and dimerize with every other member of the EGFR family. Knock-outs of Her-4 in mice show developmental defects. However, Her-4 is thought to be expressed in low quantities, if at all, in most tissues, in contrast to the other Her receptors.