Ipratropium



Ipratropium
Systematic (IUPAC) name
[8-methyl-8-(1-methylethyl)- 8-azoniabicyclo[3.2.1] oct-3-yl] 3-hydroxy-2-phenyl-propanoate
Identifiers
CAS number 60205-81-4
ATC code R03BB01
PubChem 43232
DrugBank APRD00537
Chemical data
O3 
Mol. mass 389.457 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 0 to 9% in vitro
Metabolism Hepatic
Half life 2 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

B(US)

Legal status

POM(UK)

Routes Inhalation

Ipratropium (as ipratropium bromide, trade name Atrovent) is an blood-brain barrier, which prevents central side effects (anticholinergic syndrome).

Ipratropium is also combined with albuterol (Combivent and Duoneb) for the management of COPD and asthma. Ipratropium is also combined with fenoterol (trade names Duovent and Berodual N) for the management of asthma.

Side effects are as those for other anticholinergics.

Sources

  • Brenner, G. M. (2000). Pharmacology. Philadelphia, PA: W.B. Saunders Company. ISBN 0-7216-7757-6
  • Canadian Pharmacists Association (2000). Compendium of Pharmaceuticals and Specialties (25th ed.). Toronto, ON: Webcom. ISBN 0-919115-76-4
  • Boehringer Ingelheim
v • d • e
Phenylephrine
v • d • e
Drugs for obstructive airway diseases: asthma/COPD (Ipratropium/salbutamol
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ipratropium". A list of authors is available in Wikipedia.