Mesoridazine



Mesoridazine
Systematic (IUPAC) name
10-{2-[(RS)1-Methylpiperidin-2-yl]ethyl}-2-methylsulfinyl-10H-phenothiazine
Identifiers
CAS number 5588-33-0
ATC code N05AC03
PubChem 4078
DrugBank APRD00610
Chemical data
S2 
Mol. mass 386.576 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 4%
Metabolism Hepatic/Renal
Half life 24 to 48 hours
Excretion Biliary and renal
Therapeutic considerations
Pregnancy cat.

C(US)

Legal status

℞ Prescription only

Routes oral, intravenous

Mesoridazine besylate (sold as Serentil) is a phenothiazines.

Mesoridazine partially derives its name from the prefix "Meso"[citation needed] which means "middle" which is the center of the brain called the limbic system where most dopaminergic activity takes place. The middle of the brain also contains the pineal gland and hypothalamus.

For further information see: Phenothiazine

Mesoridazine was withdrawn from the United States market in 2004.

v • d • e
Psycholeptics: antipsychotics (Zotepine)

References

  1. ^ "Facts and Comparisons" III W. Port Plaza, Suite 300 St. Louis MO. USA 63146-3098 (telephone 314-216-2100 or 1-800-223-0554). (Note this book is currently used by Rite Aid Pharmacies in the USA as a reference aid and it is a loose bound updatable book. The updatable section called "Antipsychotic Agents" is (c)1990
 
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