Neomycin


Neomycin
Systematic (IUPAC) name
?
Identifiers
CAS number	1404-04-2
ATC code	S03AA01
PubChem	8378
DrugBank	APRD00013
Chemical data
O₁₃
Mol. mass	614.644 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	2 to 3 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Neomycin is an antibiotic that is found in many topical medications such as creams, ointments and eyedrops.

Uses

Neomycin is overwhelmingly used as a aminoglycosides. The exception to this, is when it is included in some vaccines as a preservative, but in very small quantities -typically 0.025 mg per dose[1].

Spectrum

Similar to other aminoglycosides, neomycin has excellent activity against Gram negative bacteria, and has partial activity against Gram positive bacteria. It is relatively toxic to humans, and some people have allergic reactions to it.^[1] See: Hypersensitivity.

History

Neomycin was discovered in 1949 by the microbiologist Selman Waksman and his student Hubert Lechevalier. It is produced naturally by the bacterium Streptomyces fradiae.

References

^ DermNet dermatitis/neomycin-allergy

v • d • e Stomatological preparations (Amlexanox

v • d • e Rifaximin) Sulfonamides (Phthalylsulfathiazole, Sulfaguanidine, Succinylsulfathiazole) other (Beclometasone) antiallergic agents, excluding corticosteroids (Cromoglicic acid) Balsalazide)
Antidiarrheal micro-organisms	Saccharomyces boulardii
Other antidiarrheals	Albumin tannate - Ceratonia - Racecadotril

v • d • e Metronidazole

v • d • e Amikacin

v • d • e Throat preparations (Lidocaine - Cocaine - Dyclonine

v • d • e Otologicals (Lidocaine - Cocaine

Aminoglycoside antibiotics

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Neomycin". A list of authors is available in Wikipedia.