Protamine



protamine 1
Identifiers
Symbol PRM1
Entrez 5619
HUGO 9447
OMIM 182880
RefSeq NM_002761
UniProt P04553
Other data
Locus Chr. 16 p13.13
protamine 2
Identifiers
Symbol PRM2
Entrez 5620
HUGO 9448
OMIM 182890
RefSeq NM_002762
UniProt P04554
Other data
Locus Chr. 16 p13.13

Protamines are small, DNA stabilization.

Function

When mixed with NPH insulin).

heparin.[1]

Examples

Mice, humans, and certain fish have 2 or more different protamines, whereas the sperm of bull, boar, rat, rabbit, guinea pig, and ram have one form of protamine.

Human

The 2 human protamines are denoted PRM1 and PRM2.

Fish

Examples of protamines from fish are:

  • salmine from salmon
  • clupeine from herring sperm (Clupea)
  • iridine from rainbow trout
  • thinnine from tunafish (Thunnus)
  • stelline from starry sturgeon (Acipenser stellatus)
  • scylliorhinine from dogfish (Scylliorhinus)

References

  1. ^ Byun Y, Chang LC, Lee LM, Han IS, Singh VK, Yang VC (2000). "Low molecular weight protamine: a potent but nontoxic antagonist to heparin/low molecular weight protamine". ASAIO J. 46 (4): 435–9. PMID 10926141.
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Protamine". A list of authors is available in Wikipedia.