Tacalcitol



Tacalcitol
Systematic (IUPAC) name
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5R)-5-hydroxy-6-methylheptan-2-yl

]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methyli denecyclohexane-1,3-diol

Identifiers
CAS number 57333-96-7
ATC code  ?
PubChem 5283734
Chemical data
O3 
Mol. mass 416.64
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Topical

Tacalcitol is a synthetic vitamin D3 analogue that is used to treat psoriasis. Tacalcitol exerts its biological activity by preventing the proliferation of keratinocytes. Tacalcitol is marketed under several names, including Curatoderm and Bonalfa.

References

  • The Merck Index, 12th Edition. 9197