Transient receptor potential channel



Transient receptor potential or TRP channels are a family of loosely related magnesium. TRP channels are so named because they were discovered in mutant drosophila that, instead of having sustained photoreceptor activity in response to light, have only a transient response to light. Most TRP channels are comprised of 6 membrane-spanning helices with intracellular N- and C-termini. TRP channels are activated and regulated by a wide variety of stimuli and are expressed widely throughout the body.

Genes

They are encoded by at least 33 channel subunit genes divided into six sub-families:

v • d • e
Ligand-gated ion channel • Cyclic nucleotide-gated ion channel (α1, α3, β3, H1, H2, H4) • Stretch-activated ion channel
 
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