5-MeO-DMT



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5-MeO-DMT
Systematic (IUPAC) name
2-(5-methoxy-1H-indol-3-yl)-N,N-dimethylethanamine
Identifiers
CAS number 1019-45-0
ATC code  ?
PubChem 1832
Chemical data
O 
Mol. mass 218.298 g/mol
SMILES search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

Class A(UK) Schedule I(US)

Routes Smoked, Insufflated

5-MeO-DMT is a very powerful psychedelic entheogen by South American shamans for thousands of years.

Chemistry

5-MeO-DMT was first synthesized in 1936, and in 1959 it was isolated as one of the psychoactive ingredients of analogue of that compound.

History

Traditionally 5-MeO-DMT has been used in Colorado River Toad (Bufo alvarius), although there is no direct evidence this was used as a hallucinogen until recent times.

Use and effects

 This section may contain original research or unverified claims.
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When used as a Jonathan Ott, 5-MeO-DMT is active orally with doses over 30 mg without aid of a MAOI.

The onset of effects occurs in seconds after smoking/injecting, or minutes after insufflating, and the experience is sometimes described as similar to a near-death experience. Peak effects last for approximately 5-10 minutes, when smoked. When insufflated, the peak effects are considerably less intense, but last for 15-25 minutes on average.

Although similar in many respects to its close relatives DMT and bufotenin (5-OH-DMT), the effects are typically not as visual. Some users report experiencing no visual effects from it even at very high doses.[2]
Some report the effects to be unpleasant causing nausea and the feeling of being "sat on by an elephant".[3]

Erowid lists the following effects for smoked 5-MeO-DMT:[2]

Positive

  • immersive experiences
  • powerful "rushing" sensation
  • radical perspective shifting
  • profound life-changing spiritual experiences
  • some people experience erotic / sensual enhancement
  • occasional euphoria
  • internal visions (actual visual effects not as common)
  • journey into mind

Neutral

  • short duration
  • change in perception of time
  • experience of "the void"
  • lack of memory of experience
  • muscle jerking, twitching[disambiguation needed], abnormal vocalizations
  • unconsciousness / nonresponsiveness lasting 5-20 minutes
  • dissociation

Negative

  • overly-intense experiences
  • nausea[3]
  • sense of pressure in the body[3]
  • hard on the lungs to smoke
  • difficulty integrating experiences
  • fear, terror and panic
  • dysphoria (bad feelings)
  • fast onset and intensity can lead to problems if not prepared (dropped pipe, knocking things over, falling & hitting head, etc)

Legality

International Law

Denmark

As of December 1, 2004, 5-MeO-DMT is legally restricted to "medical or scientific purposes". See EMCDDA.

Germany

Schedule I / Highest level of control, unable to be prescribed, manufactured, or possessed as of Sep, 1999. (listed as [2-(5-Methoxyindol-3-yl)ethyl]dimethylazan) (see Deutsche BtMG or http://www.silicium-sensei.de/projecte/drugs/news/news.html)

Greece

5-MeO-DMT became a controlled substance in Greece on Feb 18, 2003 [EU Legal Database].

New Zealand

5-MeO-DMT is Schedule I (Class A) in New Zealand.

Sweden

Controlled in Sweden as of Oct 1, 2004 (see notisum.se)

Switzerland

5-MeO-DMT is Schedule I in Switzerland. [unconfirmed]

US State Law

Nebraska

Schedule I (Reference)

S. Dakota

Schedule I : 5-methoxy-N, N-Dimethyltryptamine. Feb 2003

See also

References

  1. ^ Pharmanopo-Psychonautics: Human Intranasal, Sublingual, Intrarectal, Pulmonary and Oral Pharmacology of Bufotenine by Jonathan Ott, The Journal of Psychoactive Drugs, September 2001
  2. ^ a b Erowid. Effects.
  3. ^ a b c Psychecelic Chemistry by Michael Valentine Smith, Page 40, ISBN 0915179105
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Drugs from TiHKAL

AL-LAD • DBT • DET • DiPT • 5-MeO-α-MT • DMT • 2,α-DMT • α,N-DMT • DPT • EiPT • α-ET • ETH-LAD • Harmaline • Harmine • 4-HO-DBT • 4-HO-DET • 4-HO-DiPT • 4-HO-DMT • 5-HO-DMT • 4-HO-DPT • 4-HO-MET • 4-HO-MiPT • 4-HO-MPT • 4-HO-pyr-T • Ibogaine • LSD • MBT • 4,5-MDO-DiPT • 5,6-MDO-DiPT • 4,5-MDO-DMT • 5,6-MDO-DMT • 5,6-MDO-MiPT • 2-Me-DET • 2-Me-DMT • Melatonin • 5-MeO-DET • 5-MeO-DiPT • 5-MeO-DMT • 4-MeO-MiPT • 5-MeO-MiPT • 5,6-MeO-MiPT • 5-MeO-NMT • 5-MeO-pyr-T • 6-MeO-THH • 5-MeO-TMT • 5-MeS-DMT • MiPT • α-MT • NET • NMT • PRO-LAD • pyr-T • Tryptamine • Tetrahydroharmine • α,N,O-TMS

v • d • e
Psychedelic tryptamines

α,N,N-TMT • 2,N,N-TMT • 5,N,N-TMT • 4-Acetoxy-DMT • 4-Acetoxy-DET • 4-Acetoxy-DIPT • 4-HO-5-MeO-DMT • α-ET • α-MT • Baeocystin • Bufotenin • DBT • DET • DIPT • DMT • DPT • EiPT • PiPT • Ethocin • Ethocybin • Iprocin • 4-HO-MET • 4-HO-MiPT • MET • MIPT • 5-Me-MIPT • 5-MeO-α-ET • 5-MeO-α-MT • 5-MeO-DALT • 5-MeO-DET • 5-MeO-DIPT • 5-MeO-DMT • 5-MeO-DPT • 5-MeO-MET • 5-MeO-MIPT • 5-MeO-α,N,N-TMT • 5-MeO-2,N,N-TMT • Miprocin • Norbaeocystin • Psilocin • Psilocybin

v • d • e
Tryptamines

4-Acetoxy-DET • 4-Acetoxy-DIPT • 4-Acetoxy-DMT • 4-HO-DIPT • 5-Bromo-DMT • 5-Fluoro-α-MT • 5-MeO-α-ET  • 5-MeO-α-MT • 5-MeO-DALT • 5-MeO-DET • 5-MeO-DIPT • 5-MeO-DMT • 5-MeO-DPT • 5-MeO-MIPT • α-ET • α-MT • Baeocystin • Bufotenin • DET • DiPT • DMT • DPT • Ethocybin • EiPT • Ethocin • Ibogaine • Iprocin • MET • MiPT • Miprocin • Melatonin • NMT • Norbaeocystin • Normelatonin • PiPT • Psilocin • Psilocybin • Rizatriptan • Serotonin • Sumatriptan • Tryptamine • Tryptophan

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "5-MeO-DMT". A list of authors is available in Wikipedia.