List of bestselling drugs



The following is a list of the top 200 pharmaceutical products ranked by sales.

Rank 2006 Brand Name(s) Generic Name Sales 2006 (USD millions) Change from 2005 Company(ies) Disease/Medical Use First Approval Date
1LipitorAstellas PharmaCholesterolDec-1996
2Advair, SeretideGlaxoSmithKlineAsthmaAug-2000
3Plavix, IscoverSanofi-AventisThrombotic eventsNov-1997
4NexiumAstraZenecaGastrointestinal disordersMar-2000
5NorvascPfizer HypertensionJul-1992
6RemicadeSchering-Plough, TanabeRheumatoid arthritisAug-1998
7EnbrelWyethRheumatoid arthritisNov-1998
8ZyprexaOlanzapine4,3644%Eli Lilly SchizophreniaSep-1996
9DiovanNovartisHypertensionDec-1996
10RisperdalRisperidone4,18318%Johnson & JohnsonSchizophreniaDec-1993
11AranespAmgenAnemiaJun-2001
12Rituxan, MabTheraBiogen Idec, Chugai PharmaceuticalNon-Hodgkin’s lymphomaNov-1997
13EffexorWyethDepressionDec-1993
14Protonix, Pantozol, PantolocAltana, SolvayGastrointestinal disordersFeb-2000
15SingulairMerck & Co.AsthmaFeb-1998
16SeroquelAstellas PharmaSchizophreniaSep-1997
17Prevacid, TakepronTakeda PharmaceuticalGastrointestinal disordersMay-1995
18Procrit, EprexJohnson & JohnsonAnemiaDec-1990
19Cozaar, HyzaarMerck & Co.HypertensionApr-1995
20FosamaxMerck & Co.OsteoporosisSep-1995
21HerceptinGenentech, Chugai PharmaceuticalBreast cancerSep-1998
22Lovenox, ClexaneSanofi-AventisDeep-vein thrombosisMar-1993
23Avandia, Avandamet, AvandarylGlaxoSmithKlineType 2 diabetesMay-1999
24ActosTakeda Pharmaceutical, Eli Lilly Type 2 diabetesJul-1999
25ZocorMerck & Co.CholesterolDec-1991
26CopaxoneGlatiramer2,75719%Sanofi-AventisMultiple sclerosisDec-1996
27AcipHex, ParietJohnson & JohnsonGastrointestinal disordersAug-1999
28NeulastaAmgenNeutropeniaJan-2002
29Lexapro, CipralexH. LundbeckMajor depressive disorderAug-2002
30Gleevec, GlivecNovartisLeukemiaMay-2001
31Ambien, StilnoxSanofi-AventisInsomniaDec-1992
32AriceptPfizerAlzheimer’s diseaseNov-1996
33EpogenAmgenAnemiaJun-1989
34Zyrtec, CirrusDaiichi SankyoAllergic rhinitisDec-1995
35Avapro, Aprovel, AvalideBristol-Myers SquibbHypertensionSep-1997
36AvastinGenentechColorectal cancerFeb-2004
37TaxotereSanofi-AventisCancerOct-1995
38Eloxatin, EloxatineSanofi-AventisColorectal cancerAug-2002
39ZoloftPfizer DepressionDec-1991
40TamifluOseltamivir2,09669%Roche, Chugai PharmaceuticalInfluenzaOct-1999
41LantusSanofi-AventisType 2 diabetes and type 1 diabetesApr-2000
42CrestorAstraZeneca, ShionogiCholesterolNov-2002
43HumiraAbbott LaboratoriesRheumatoid arthritisDec-2002
44CelebrexPfizer Osteoarthritis and rheumatoid arthritisDec-1998
45TopamaxJohnson & JohnsonSeizuresDec-1996
46Prevnarvaccine1,96130%WyethPneumococcal diseaseFeb-2000
47VytorinSchering-PloughCholesterol Jul-2004
48ZetiaSchering-PloughCholesterol Oct-2002
49WellbutrinBiovailDepressionAug-2003
50AbilifyBristol-Myers SquibbSchizophreniaNov-2002
51LamictalGlaxoSmithKlineSeizuresDec-1994
52Toprol, SelokenAstraZenecaHypertensionJan-1992
53NeoRecormon, EpoginErythropoietin1,777-1%Roche, Chugai PharmaceuticalAnemiaJul-1997
54Atacand, BlopressAstraZenecaHypertensionOct-1997
55SpirivaBoehringer IngelheimChronic obstructive pulmonary diseaseApr-2002
56AvonexBiogen Idec Multiple sclerosisMay-1996
57ViagraPfizer Erectile dysfunctionMar-1998
58MicardisAstellas PharmaHypertensionNov-1998
59ActonelSanofi-AventisOsteoporosisMar-1998
60Lupron, LeuplinTakeda Pharmaceutical, TAP PharmaceuticalsProstate cancerJan-1989
61TriCor, LipanthylAbbott Laboratories, SolvayCholesterolFeb-1998
62ZofranGlaxoSmithKlineNausea and vomitingDec-1992
63ValtrexGlaxoSmithKlineHerpesJun-1995
64Levaquin, FloxinJohnson & Johnson Bacterial infectionsDec-1996
65ArimidexAstraZenecaBreast cancerDec-1995
66PrografAstellas PharmaTransplant rejectionApr-1993
67CellCeptMycophenolate mofetil1,4708%Roche, Chugai PharmaceuticalTransplant rejectionMay-1995
68Xalatan, XalacomPfizer Intraocular pressureJun-1996
69RebifSeronoMultiple sclerosisFeb-1998
70CoregGlaxoSmithKlineHypertensionSep-1995
71GemzarGemcitabine1,4085%Eli Lilly CancerMay-1996
72Prilosec, LosecAstraZenecaGastrointestinal disordersSep-1989
73Benicar, OlmetecForest LaboratoriesHypertensionApr-2002
74LotrelNovartisHypertensionJun-1999
75CymbaltaDuloxetine1,31694%Eli LillyDepressive disorderAug-2004
76Imitrex, ImigranGlaxoSmithKlineMigraineDec-1992
77DepakoteAbbott LaboratoriesSeizuresMar-1983
78HumalogInsulin analog1,3008%Eli Lilly DiabetesApr-1996
79DuragesicJohnson & JohnsonPainAug-1990
80PulmicortAstraZenecaAsthmaJun-1997
81ZometaNovartisHypercalcemiaAug-2000
82Betaseron, BetaferonSchering AGMultiple sclerosisJul-1993
83Delix, TritaceSanofi-AventisHypertensionJul-2000
84Flovent, FlixotideGlaxoSmithKlineAsthmaMar-1996
85NeupogenAmgenNeutropeniaFeb-1991
86CasodexAstraZenecaProstate cancerOct-1995
87PravacholBristol-Myers SquibbCholesterolOct-1991
88TruvadaGilead SciencesHIV infectionAug-2004
89SymbicortAstraZenecaAsthmaAug-2000
90PegasysPegylated interferon alfa-2a1,1715%Roche, Chugai PharmaceuticalHepatitis CJun-2002
91EvistaRaloxifene1,1594%Eli Lilly, Chugai PharmaceuticalOsteoporosisDec-1997
92FlomaxBoehringer IngelheimBenign prostatic hypertrophyOct-1997
93LyricaPfizerNeuropathic painJul-2004
94Paxil, SeroxatGlaxoSmithKlineDepressionDec-1992
95KaletraAbbott LaboratoriesHIV infectionMar-2001
96DetrolPfizer Overactive bladderMar-1998
97HarnalAstellas PharmaBenign prostatic hypertrophyJul-1992
98ErbituxMerck KGaAColorectal cancerFeb-2004
99SynagisPalivizumab1,065-9%MedImmuneRespiratory syncytial virusJun-1998
100AugmentinGlaxoSmithKlineBacterial infectionsAug-1984
101Premarin, Prempro, PremphaseWyethMenopausal symptomsNov-1995
102Ortho contraceptivesJohnson & JohnsonContraceptionApr-1984
103ZoladexAstraZenecaProstate cancerDec-1989
104CerezymeImiglucerase1,0078%Genzyme Gaucher diseaseApr-1991
105CravitDaiichi Sankyo, Santen PharmaceuticalBacterial infectionsJun-1909
106YasminSchering AGPrevention of pregnancyAug-2000
107KogenateRecombinant factor VIII98919%Bayer HemophiliaFeb-1993
108BotoxBotulin toxin98218%Allergan Cervical dystoniaDec-1989
109LamisilNovartisFungal infectionsDec-1992
110CombivirGlaxoSmithKlineHIV infectionSep-1997
111Zosyn, TazocinPiperacillin9729%WyethBacterial infectionsOct-1993
112CialisTadalafil97130%Lilly, Lilly IcosErectile dysfunctionNov-2002
113KeppraLevetiracetam95636%UCB SeizuresNov-1999
114NovoSevenFactor VII94811%Novo Nordisk Bleeding due to hemophiliaFeb-1996
115Infanrix, Pediarixvaccine94521%GlaxoSmithKlineDiphtheria, tetanus, and pertussisJan-1996
116NasonexMometasone94428%Schering-Plough Allergic rhinitisOct-1997
117ReyatazAtazanavir93134%Bristol-Myers SquibbHIV infectionJan-2003
118ConcertaJohnson & JohnsonAttention-deficit hyperactivity disorderAug-2000
119HumulinRecombinant human insulin925-8%Eli Lilly DiabetesOct-1982
120Neoral, SandimmunNovartisTransplant rejectionJul-1995
121SandostatinNovartisAcromegalyOct-1988
122CamptosarPfizer Colorectal cancerJun-1996
123Engerix-B, Havrix, Twinrixvaccine88610%GlaxoSmithKlineHepatitisAug-1989
124Allegra, TelfastSanofi-AventisAllergic rhinitisJul-1996
125AdderallShire PharmaceuticalsAttention-deficit hyperactivity disorderOct-2001
126CombiventBoehringer IngelheimChronic obstructive pulmonary diseaseOct-1996
127Peg-IntronPegylated interferon alfa-2b83711%Schering-Plough Hepatitis CMay-2000
128AdalatBayer HypertensionNov-1985
129Avelox, AvaloxSchering-Plough, ShionogiBacterial infectionsDec-1999
130MobicDaiichi SankyoOsteoarthritis and rheumatoid arthritisFeb-1996
131BiaxinAbbott LaboratoriesBacterial infectionsOct-1991
132MevalotinDaiichi Sankyo CholesterolJun-1909
133Ultane, SevoraneAbbott LaboratoriesAnesthesiaJun-1995
134GenotropinPfizer Growth failureAug-1995
135SustivaBristol-Myers SquibbHIV infectionSep-1998
136ZyvoxPfizerBacterial infectionsApr-2000
137XelodaCapecitabine77522%Roche, Chugai PharmaceuticalCancerJun-1909
138Geodon, ZeldoxPfizer SchizophreniaFeb-2001
139Cipro, CiprobaySchering-PloughBacterial infectionsOct-1987
140ProvigilCephalonSleepinessDec-1998
141LescolNovartisCholesterolDec-1993
142Clarinex, AeriusSchering-Plough Allergic rhinitisDec-2001
143FemaraNovartis, Chugai PharmaceuticalBreast cancerJul-1997
144TrileptalNovartisSeizuresNov-1999
145TracleerBosentan71742%ActelionPulmonary arterial hypertensionNov-2001
146PrimaxinMerck & Co.Bacterial infectionsNov-1985
147TemodarSchering-PloughAnaplastic astrocytomaAug-1999
148Trusopt, CosoptMerck & Co.Intraocular pressureDec-1994
149VoltarenNovartisOsteoarthritis and rheumatoid arthritisJul-1998
150VireadGilead SciencesHIV infectionOct-2001
151SifrolBoehringer IngelheimParkinson’s diseaseOct-1997
152NamendaForest LaboratoriesAlzheimer diseaseOct-2003
153AltaceKing PharmaceuticalsCardiovascular eventsJan-1991
154ByettaExenatide649464%Amylin Pharmaceuticals, Eli Lilly Type 2 diabetesApr-2005
155TarcevaGenentechNon-small cell lung cancerNov-2004
156Zithromax, ZmaxPfizer Bacterial infectionsNov-1991
157OmnicefAbbott LaboratoriesBacterial infectionsDec-1997
158ProscarMerck & Co.Benign prostatic hypertrophyJun-1992
159AlimtaPemetrexed61232%Eli LillyNon-small cell lung cancerFeb-2004
160MerremAstraZenecaBacterial infectionsJun-1996
161ForteoTeriparatide59453%Eli LillyOsteoporosisNov-2002
162StratteraAtomoxetine5795%Eli Lilly Attention-deficit hyperactivity disorderNov-2002
163ActiqCephalonCancer painNov-1998
164Flonase, FlixonaseGlaxoSmithKlineAllergic rhinitisOct-1994
165AmarylSanofi-AventisType 2 diabetesNov-1995
166LidodermEndo PharmaceuticalsPainMar-1999
167LunestaEszopiclone56772%SepracorInsomniaDec-2004
168Boniva, BonvivaGlaxoSmithKlineOsteoporosisMar-2005
169TaxolBristol-Myers SquibbCancerDec-1992
170Zelnorm, ZelmacNovartisIrritable bowel syndromeMar-2002
171RenagelSevelamer55923%Genzyme, Roche, Chugai PharmaceuticalHyperphosphatemiaOct-1998
172NorditropinHuman growth hormone55719%Novo Nordisk Growth hormone deficiencyJun-1909
173XopenexLevalbuterol55529%SepracorBronchospasmMar-1999
174XenicalOrlistat5539%RocheObesityJul-1998
175Vasotec, VasereticMerck & Co.HypertensionDec-1985
176SereventGlaxoSmithKlineAsthmaFeb-1994
177CarduraPfizer HypertensionNov-1990
178SynthroidAbbott LaboratoriesHypothyroidismMay-1909
179Gonal-fSeronoInfertilityOct-1995
180GasterAstellas PharmaGastrointestinal disordersJun-1909
181CancidasMerck & Co.Fungal infectionsJan-2001
182ExelonNovartisAlzheimer’s diseaseMay-1998
183VfendPfizerFungal infectionsMar-2002
184AmlodinAmlodipine5064%Dainippon SumitomoHypertension, angina pectorisn/a
185NiaspanNiacin49813%Kos PharmaceuticalsCholesterolJul-1997
186NeurontinPfizer SeizuresDec-1993
187TrizivirGlaxoSmithKlineHIV infectionNov-2000
188RequipGlaxoSmithKlineParkinson diseaseSep-1997
189Follistim, PuregonFollitropin beta4828%Akzo NobelInfertilitySep-1997
190BasenTakeda PharmaceuticalHyperglycemiaJun-1909
191LevitraGlaxoSmithKlineErectile dysfunctionMar-2003
192GlucophageBristol-Myers SquibbType 2 diabetesDec-1994
193ConcorMerck KGaAHypertensionJul-1992
194Epzicom, KixevaGlaxoSmithKlineHIV infectionAug-2004
195XatralSanofi-AventisBenign prostatic hypertrophyJan-2000
196DiflucanPfizer Fungal infectionsJan-1990
197ThalomidThalidomide43312%CelgeneErythema nodosum leprosum Jul-1998
198ZantacGlaxoSmithKline Gastrointestinal disordersJun-1983
199XolairGenentechAsthmaJun-2003
200ClaritinSchering-Plough, ShionogiAllergic rhinitisApr-1993

Source: MedAdNews 200 - World's Best-Selling Medicines, MedAdNews, July 2007

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "List_of_bestselling_drugs". A list of authors is available in Wikipedia.