Mianserin



Mianserin
Systematic (IUPAC) name
 ?
Identifiers
CAS number 24219-97-4
ATC code N06AX03
PubChem 4184
Chemical data
N2 
Mol. mass 264.365
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Mianserin is a Mirtazapine.

Mianserin blocks inhibitory α2-autoreceptors on central noradrenergic nerve endings, and so may increase the amount of noradrenaline in the synaptic cleft. It may also cause agranulocytosis and aplastic anaemia.

Mianserin has been shown to increase the lifespan of the nematode C. elegans by 30%.[1] [2]


References

  1. ^ Antidepressant Found To Extend Lifespan In C. elegans http://www.sciencedaily.com/releases/2007/11/071121144946.htm
  2. ^ An antidepressant that extends lifespan in adult Caenorhabditis elegans http://www.nature.com/nature/journal/v450/n7169/abs/nature05991.html
v • d • e
Psychoanaleptics: RIs
S RI Trazodone)
A RI Maprotiline)
D RI Amineptine)
SN RI Venlafaxine
ND RI Bupropion
SND RI Nomifensine
Mirtazapine)
 
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