Nimetazepam



Nimetazepam
Systematic (IUPAC) name
2-methyl-9-nitro-6-phenyl-
2,5-diazabicyclo[5.4.0]undeca-5,8,10,12-tetraen-3-one
Identifiers
CAS number 2011-67-8
ATC code N05
PubChem 4496
DrugBank ?
Chemical data
O3 
Mol. mass 295.3
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life  ?
Excretion Renal
Therapeutic considerations
Pregnancy cat.

X

Legal status

Schedule IV(US)

Routes Oral

Nimetazepam (marketed under brand name Erimin®) is a skeletal muscle relaxant properties. It is sold in 5 mg tablets known as Erimin-5. It is used to treat insomnia.

Nimetazepam has a reputation for being particularly subject to abuse (known as 'Happy 5', sold as an Ecstasy replacement without a hangover), especially by persons addicted to nitrazepam instead.[1]

In a rat study Nimetazepam showed greater damage to the fetus, as did temazepam when compared against other benzodiazepines. Diazepam however showed relatively weak fetal toxicities.[2]

See also

References

  1. ^ http://www.usdoj.gov/dea/programs/forensicsci/microgram/journal2004/page27.html
  2. ^ Saito H; Kobayashi H, Takeno S, Sakai T. (1984). "Fetal toxicity of benzodiazepines in rats.". Res Commun Chem Pathol Pharmacol. 46 (3): 437-47. PMID 6151222.
v • d • e
N05CD)
1,4-Benzodiazepines
Triazolobenzodiazepines
Imidazobenzodiazepines
Oxazolobenzodiazepines
ThienobenzodiazepinesZolazepam
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Psycholeptics: Valnoctamide
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nimetazepam". A list of authors is available in Wikipedia.