Myristicin



Myristicin[1]
IUPAC name 4-Methoxy-6-prop-2-enyl-benzo[1,3]dioxole
Other names 5-Allyl-1-methoxy-2,3-(methylenedioxy)benzene
Identifiers
CAS number 607-91-0
PubChem 4276
EINECS number 210-146-9
SMILES COC1=CC(=CC2=C1OCO2)CC=C
Properties
Molecular formula C11H12O3
Molar mass 192.211 g/mol
Appearance Colorless oil
Density 1.1437 g/cm³ at 20 °C
Melting point

<25 °C

Boiling point

173 °C (40 mmHg)

Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Myristicin, 3-methoxy,4,5-methylendioxy-allylbenzene, is a natural monoamine oxidase.[2][3]

Uses

In 1963 by safrole to piperonylic acid.

Intoxications with myristicin or MDMA. Effects vary from person to person, but are often reported to be a state somewhere between waking and dreaming; nausea is often experienced, but some report that using cannabis can offset the nausea.[5]

In addition to a semi-conscious state, myristicin also has been known to induce psychoactive or hallucinogenic effects.[citation needed] The dosage required to achieve such an effect varies from person to person and from source to source. The average dosage required to obtain these effects are somewhere in the region of 15 to 25 g of ground fresh nutmeg. This will vary with each nut.

References

  1. ^ Merck Index, 12th Edition, 6417.
  2. ^ Truitt EB, Duritz G, Ebersberger EM (1963). "Evidence of monoamine oxidase inhibition by myristicin and nutmeg". Proc. Soc. Exp. Biol. Med. 112: 647-50. PMID 13994372.
  3. ^ Lee BK, Kim JH, Jung JW, Choi JW, Han ES, Lee SH, Ko KH, Ryu JH (2005). "Myristicin-induced neurotoxicity in human neuroblastoma SK-N-SH cells". Toxicol. Lett. 157 (1): 49-56. PMID 15795093.
  4. ^ The Use of Nutmeg as a Psychotropic Agent by Andrew Weil at lycaeum.org
  5. ^ See Erowid: Nutmeg for various primary and secondary sources related to nutmeg/myristicin intoxication.


 
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