Chlorphentermine


Chlorphentermine
Systematic (IUPAC) name
1-(4-chlorophenyl)-2-methylpropan-2-amine
Identifiers
CAS number	461-78-9 151-06-4 (HCl)
ATC code	A08AA
PubChem	10007
Chemical data
N
Mol. mass	183.68 g/mol
Synonyms	p-Chloro-α,α-dimethylphenethylamine
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	40 hours
Excretion	Renal
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Oral

Chlorphentermine (trade names Apsedon, Desopimon, Lucofen) is a phentermine,^[1] which is still in current use.

Chlorphentermine itself is a relatively weak stimulant with little abuse potential, but is classed as a Schedule 3 drug in the USA due mainly to its similarity to other appetite suppressants such as aminorex which were found to cause pulmonary hypertension and cardiac fibrosis following prolonged use.^[2]

References

^ Gylys JA, Hart JJ, Warren MR. Chlorphentermine, a new anorectic agent. Journal of Pharmacology and Experimental Therapeutics. 1962 Sep;137:365-73.
^ Rothman RB, Ayestas MA, Dersch CM, Baumann MH. Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. Circulation. 1999 Aug 24;100(8):869-75.

Theophylline
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Piperazines	BZP • MeOPP • MBZP • mCPP • 2C-B-BZP
Tropanes	Brasofensine • CFT • Cocaethylene • Cocaine • Lometopane • RTI-121 • Tesofensine • Troparil
Thujone
Phenylaminooxazoles	4-Methyl-aminorex • Aminorex • Clominorex • Fenozolone • Fluminorex • Pemoline • Thozalinone
Others	Amineptine • Bemegride • BPAP • Clenbuterol • Clofenciclan • Cyclopentamine • Cyprodenate • Desoxypipradrol • Ethylphenidate • Ethamivan • Gilutensin • GYKI-52895 • Hexacyclonate • Indanorex • Indatraline • Isometheptene • Mazindol • MDPV • Mesocarb • Dexmethylphenidate) • Naphthylisopropylamine • Nikethamide • Nocaine • Nomifensine • Phacetoperane • Phthalimidopropiophenone • Pipradrol • Prolintane • Propylhexedrine • Pyrovalerone • Sibutramine • Tuamine • Vanoxerine • Yohimbine • Zylofuramine
See also Sympathomimetic amines

Categories: Serotonin receptor agonists

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Chlorphentermine". A list of authors is available in Wikipedia.