Ethylphenidate



Ethylphenidate
Systematic (IUPAC) name
ethyl 2-phenyl-2-piperidin-2-ylacetate
Identifiers
CAS number 57413-43-1
ATC code  ?
PubChem 3080846
Chemical data
O2 
Mol. mass 247.33274 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes N/A

Ethylphenidate is a cocaethylene.

Ethylphenidate is a more selective noradrenaline reuptake inhibitor.[4]



References

  1. ^ Markowitz JS, DeVane CL, Boulton DW, Nahas Z, Risch SC, Diamond F, Patrick KS. Ethylphenidate formation in human subjects after the administration of a single dose of methylphenidate and ethanol. Drug Metabolism and Disposition. 2000 Jun;28(6):620-4.
  2. ^ Markowitz JS, Logan BK, Diamond F, Patrick KS. Detection of the novel metabolite ethylphenidate after methylphenidate overdose with alcohol coingestion. Journal of Clinical Psychopharmacology. 1999 Aug;19(4):362-6.
  3. ^ Patrick KS, Williard RL, VanWert AL, Dowd JJ, Oatis JE Jr, Middaugh LD. Synthesis and pharmacology of ethylphenidate enantiomers: the human transesterification metabolite of methylphenidate and ethanol. Journal of Medicinal Chemistry. 2005 Apr 21;48(8):2876-81.
  4. ^ Williard RL, Middaugh LD, Zhu HJ, Patrick KS. Methylphenidate and its ethanol transesterification metabolite ethylphenidate: brain disposition, monoamine transporters and motor activity. Behavioural Pharmacology. 2007 Feb;18(1):39-51.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ethylphenidate". A list of authors is available in Wikipedia.